CD105 (ENDOGLIN)-NEGATIVE MURINE MESENCHYMAL STROMAL CELLS DEFINE A NEW MULTIPOTENT SUBPOPULATION WITH DISTINCT DIFFERENTIATION AND IMMUNOMODULATORY CAPACITIES.

CD105 (endoglin)-negative murine mesenchymal stromal cells define a new multipotent subpopulation with distinct differentiation and immunomodulatory capacities.

Administration of in vitro expanded mesenchymal stromal cells (MSCs) represents a promising therapy for regenerative medicine and autoimmunity.Both mouse and human MSCs ameliorate autoimmune disease in syn-, allo- and xenogeneic settings.However, MSC preparations are heterogeneous which impairs their therapeutic efficacy and endorses variability be

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Enhancing Medical Image Classification Through PSO-Optimized Dual Deterministic Approach and Robust Transfer Learning

Effective transfer learning, within medical image classification, is probably one of the most critical areas of research due to the associated complexities with the nature of medical images.These involve variations in the acquisition techniques of images, resolutions, modalities, and patient demographics.This study aims to develop a robust transfer

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The Evolutionary Volte-Face of Transposable Elements: From Harmful Jumping Genes to Major Drivers of Genetic Innovation

Transposable elements (TEs) are self-replicating DNA elements that constitute major fractions of eukaryote genomes.Their ability to transpose can modify the genome structure with potentially deleterious effects.To repress TE activity, host cells have developed numerous strategies, including epigenetic pathways, such as DNA methylation or histone mo

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